Publications

Select Peer-reviewed publications

Komsky-Elbaz A, Shuhmaher M, Sanchez-Lopez JA, Teena O, Waiger D, Zelinger E, Kossobsky T, Otikovs L, Dilevsky E, Soen Y, Hefetz A, Heifetz Y (2025). Extracellular vesicles, lipid droplets and AhR ligands in early implantation: the dynamics of embryo-maternal cross talk. J. Extracell. Vesicles. 14.5 11, e70161.

Chen DS, Marrero K, Sanchez-Lopez JA, Belenky M, Thomalla JM, Buehner NA, Apel I, Levi Y, Hafezi Y, Wang S, Clark AG, Heifetz Y, Siegal ML, Wolfner MF (2025). The paired spermathecae sperm storage organs of Drosophila melanogaster differ in both function and developmental origin. Proc. Natl. Acad. Sci. USA. 122, e2512096122.

Zelinger E, Brumfeld V, Rechav K, Waiger D, Kossovsky T & Heifetz Y (2024) Three-dimensional correlative microscopy of the Drosophila female reproductive tract reveals modes of communication in seminal receptacle sperm storage. Commun. Biol. 7, 155.

Guzewska MM, Myszczynski K, Heifetz Y, Kaczmarek MM (2023) Embryonic signals mediate extracellular vesicle biogenesis and trafficking at the embryo-maternal interface. Cell Commun. Signal. 21, 210.

Sanchez-Lopez JA, Twena S, Apel I, Kornhaeuser SC, Chasnitsky M, Miklosi AG, Vega-Dominguez PJ, Shephard A, Hefetz A & Heifetz Y (2022) Male-female communication enhances release of extracellular vesicles leading to high fertility. Commun. Biol. 815.

Szuszkiewicz J, Myszczynski K, Reliszko ZP, Heifetz Y & Kaczmarek, MM (2022) Early steps of embryo implantation are regulated by exchange of extracellular vesicles between the embryo and the endometrium. FASEB J. 36, e22450.

McQueen EW, Afkhami M, Atallah J, Belote JM, Gompel, N., Heifetz Y, Kamimura Y, Kornhauser SC, Masly JP, O’Grady P, Peláez J, Rebeiz M, Rice G, Sánchez-Herrero E, Santos Nunes MD, Rampasso AS, Schnakenberg SL, Siegal ML, Takahashi A, Tanaka KM, Turetzek N, Zelinger E, Courtier-Orgogozo V, Toda MJ, Wolfner MF & Yassin A (2022) A standardized nomenclature and atlas of the female terminalia of Drosophila melanogaster. FLY, 16, 128–151.

Kaczmarek MM, Reliszko SP, Szuszkiewicz J, Nitkiewicz A, Guzewska MM, Myszczynski K, Romaniewicz M, Sikora M, Kajko M & Heifetz Y (2021). Profiling circulating microRNAs in serum of pregnant and non-pregnant pigs reveals a plethora of reproductive status-dependent microRNAs. Animal 15, 100182.

Heifetz Y., Tram U. (2017) Oogenesis, final oocyte maturation & ovulation, Insects. Encyclopedia of Reproduction, 2nd Edition, Vol 6. Elsevier.

Elgart M., Stern S., Salton O., Gnainsky Y., Heifetz Y., Soen Y. (2016) Impact of gut microbiota on the fly’s germ line. Nature communication 7, 11280.

Avila F.W., Sanchez-Lopez J.A., McGlaughon J.L., Raman S., Wolfner M.F., Heifetz Y. (2016) Nature and functions of glands and ducts in the Drosophila reproductive tract. In: Extracellular Composite Matrices in Arthropods. Edited by Ephraim Cohen, Bernard Moussian. Springer, International Publishers, Switzerland, pp. 411-444.

Carmel I., Tram U., Heifetz Y. (2016) Mating induces developmental changes in the insect female reproductive tract. Curr Opin Insect Sci 13, 106-1013.

Heifetz, Y., Wolfner, M.F. (2015) Neuronal nitric oxide synthase in the lower reproductive tract of female Drosophila. Mol Reprod Dev 82, 265.

Chinnapandi, B., Raman, S., Heifetz, Y., Achiraman, S. Krishnan, M., Kamalakkannan, S. (2014) Nanovesicles mediated tumor tolerance in Dalton’s Ascites Lymphoma mice. J Stem Cell Res Ther 4, 11-15.

Heifetz, Y., Wolfner, M.F. (2014) Mating‐regulates reproductive‐tract neuromodulators in Drosophila. Mol Reprod Dev 81, 567.

Heifetz, Y., Lindner, M., Garini, Y., Wolfner, M.F. (2014) Mating regulates neuromodulator ensembles at nerve termini innervating the Drosophila reproductive tract. Curr Biol 24, 731–737.

Carmel, I., Shomron, N., Heifetz, Y. (2012) Does base-pairing strength plays a role in micro RNA repression? RNA 18, 1947-1956.

Heifetz, Y., Rivlin, P.K. (2010) Beyond the mouse model: using Drosophila as a model for sperm interaction with the female reproductive tract. Theriogenology 73, 723-739.

Kapelnikov, A., Rivlin, P.K., Hoy, R.R., Heifetz, Y. (2008) Tissue remodeling: a mating-induced differentiation program for the Drosophila oviduct. BMC Dev Biol 8, 114.

Kapelnikov, A., Zelinger, E., Gottlieb, Y., Rhrissorrakrai, K., Gunsalus, K.C., Heifetz, Y. (2008) Mating Induces an immune response and developmental switch in the Drosophila oviduct. Proc Natl Acad Sci USA 105, 13912-13917.

Pilpel, N., Nezer, I., Applebaum, S.W., Heifetz, Y. (2008) Mating increases trypsin in female Drosophila hemolymph. Insect Biochem Mol Biol.38, 320-330.

Mack, P., Kapelnikov, A., Heifetz, Y., Bender, M. (2006) Mating-responsive genes in reproductive tissues of female Drosophila melanogaster. Proc Natl Acad Sci USA 103, 10358-10363.

Heifetz, Y., Wolfner, M.F. (2004) Mating, seminal fluid components, and sperm cause changes in vesicle release in the Drosophila female reproductive tract. Proc Natl Acad Sci USA. 101, 6261-6266.

Bloch Qazi, M.C., Heifetz, Y., Wolfner, M.F. (2003) The developments between gametogenesis and fertilization: ovulation and female sperm storage in Drosophila melanogaster. Dev Biol. 256, 195-211.